Coupling of local cerebral blood flow to local cerebral glucose utilization during isoflurane and sevoflurane anesthesia.
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منابع مشابه
Role of Nitric Oxide and ATP-Sensitive K+ Channels in Regulation of Basal Blood Flow and Hypercapnic Vasodilatation of Cerebral Blood Vessels in Rabbit
Background: The mechanisms underlying cerebral hypercapnic vasodilatation are not fully understood. Objective: To investigate the role of nitric oxide (NO) and ATP-sensitive potassium (KATP) channels in basal blood flow regulation and hypercapnia-induced vasodilatation in rabbit cerebral blood vessels. Methods: The change in cerebral blood flow was measured by a laser Doppler flowmeter in 18 Ne...
متن کاملRole of Local Nerves and Prostaglandins in Regulation of Basal Blood Flow and Hypercapnic Vasodilatation of Cerebral Blood Vessels in the Rabbit
The mechanisms underlying cerebral vasodilatation during hypercapnia are not fully understood. To examine the role of nerves and prostaglandins in the regulation of basal blood flow and in hypercapnia-induced vasodilatation in the cerebral blood vessels of rabbit.Cerebral blood flow was measured by laser Doppler flow-meter in 18 NZW rabbits anesthetized with sodium pentobarbital. Tetrodetoxin ...
متن کاملDirect cerebral vasodilatory effects of sevoflurane and isoflurane.
BACKGROUND The effect of volatile anesthetics on cerebral blood flow depends on the balance between the indirect vasoconstrictive action secondary to flow-metabolism coupling and the agent's intrinsic vasodilatory action. This study compared the direct cerebral vasodilatory actions of 0.5 and 1.5 minimum alveolar concentration (MAC) sevoflurane and isoflurane during an propofol-induced isoelect...
متن کاملMild and moderate hypothermia (alpha-stat) do not impair the coupling between local cerebral blood flow and metabolism in rats.
BACKGROUND AND PURPOSE The effects of hypothermia on global cerebral blood flow (CBF) and glucose utilization (CGU) have been extensively studied, but less information exists on a local cerebral level. We investigated the effects of normothermic and hypothermic anesthesia on local CBF (LCBF) and local CGU (LCGU). METHODS Thirty-six rats were anesthetized with isoflurane (1 MAC) and artificial...
متن کاملMild and Moderate Hypothermia (a-Stat) Do Not Impair the Coupling Between Local Cerebral Blood Flow and Metabolism in Rats
Background and Purpose—The effects of hypothermia on global cerebral blood flow (CBF) and glucose utilization (CGU) have been extensively studied, but less information exists on a local cerebral level. We investigated the effects of normothermic and hypothermic anesthesia on local CBF (LCBF) and local CGU (LCGU). Methods—Thirty-six rats were anesthetized with isoflurane (1 MAC) and artificially...
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عنوان ژورنال:
- Anesthesiology
دوره 91 3 شماره
صفحات -
تاریخ انتشار 1999